产品名称

PIK 75 hydrochloride

产品货号

Axon 1334 CAS [945619-31-8] MF C16H14BrN5O4SMW 452.28 Purity: 99% Moderately soluble in DMSO Description PI3K p110α specific inhibitor; IC50 values (nM): 7.8 (p110α), 343 (p110β), 907 (p110δ) (Chaussade et al reported). KEYWORDS: PIK 75 hydrochloride | supplier | PI3K p110α inhibitor | PIK75 HCl | PIK-75 | CAS [945619-31-8] | [372196-77-5] | Phosphatidylinositol | PI3K | p110-alpha | insulin signaling

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

PIK 75 hydrochloride

Based on 474 reference(s) in Google Scholar 10 10 474

Axon 1334

CAS [945619-31-8]

MF C16H14BrN5O4S
MW 452.28

Purity: 99%
Moderately soluble in DMSO

PIK 75 hydrochloride

Description

PI3K p110α specific inhibitor; IC50 values (nM): 7.8 (p110α), 343 (p110β), 907 (p110δ) (Chaussade et al reported).

KEYWORDS: PIK 75 hydrochloride | supplier | PI3K p110α inhibitor | PIK75 HCl | PIK-75 | CAS [945619-31-8] | [372196-77-5] | Phosphatidylinositol | PI3K | p110-alpha | insulin signaling

ZA Knight et al. A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling. Cell 2006, 125, 733–747.

C Chaussade et al. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J. 2007, 404(3), 449–458.

S Kim et al. Insulin-like growth factor-1 regulates platelet activation through PI3-Kα isoform. Blood, 2007, 110(13), 4206-4213.

List of publications using PIK 75 (Axon 1334) purchased from Axon Medchem

Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153

PI3K inhibitor (p110-α specific)

Chemical name

N'-[(1E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride

Parent CAS No.

[945619-31-8]

产品资料