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产品名称 Clozapine, N-Desmethyl- - Norclozapine | Normethylclozapine | ACP-104
产品货号 Axon 2846 CAS [6104-71-8] MF C17H17ClN4MW 312.80 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Major metabolite of Clozapine (Axon 1146). N-Desmethylclozapine is a relatively potent and efficacious partial agonist at the D2 and D3 dopamine receptors, while showing inverse agonism at the 5-HT2A receptor. Moreover, N-Desmethylclozapine is a potent partial agonist at the muscarinic M1 receptor and a selective agonist at δ opioid receptor. KEYWORDS: N-Desmethylclozapine | supplier | Clozapine metabolite | Norclozapine | Normethylclozapine | ACP-104 | ACP104 | ACP 104 | CAS [6104-71-8] | Serotonin; Dopamine | D (Non Selective) | 5-HT (Non Selective) | Agonist | Receptors | Muscarinic M1 | δ Opioid
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Clozapine, N-Desmethyl- - Norclozapine | Normethylclozapine | ACP-104

Based on 16 reference(s) in Google Scholar 8 10 16

Axon 2846

CAS [6104-71-8]

MF C17H17ClN4
MW 312.80

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

Clozapine, N-Desmethyl-

Description

Major metabolite of Clozapine (Axon 1146). N-Desmethylclozapine is a relatively potent and efficacious partial agonist at the D2 and D3 dopamine receptors, while showing inverse agonism at the 5-HT2A receptor. Moreover, N-Desmethylclozapine is a potent partial agonist at the muscarinic M1 receptor and a selective agonist at δ opioid receptor.

KEYWORDS: N-Desmethylclozapine | supplier | Clozapine metabolite | Norclozapine | Normethylclozapine | ACP-104 | ACP104 | ACP 104 | CAS [6104-71-8] | Serotonin; Dopamine | D (Non Selective) | 5-HT (Non Selective) | Agonist | Receptors | Muscarinic M1 | δ Opioid

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