产品名称

Agomelatine

产品货号

Axon 1492 CAS [138112-76-2] MF C15H17NO2MW 243.30 Purity: 99% Soluble in DMSO Description Potent melatonin agonist; first melatonin antidepressant; also known as a norepinephrine dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor References Certificates Categories Extra info SA Montgomery. Major depressive disorders: clinical efficacy and tolerability of agomelatine, a new melatonergic agonist. Eur. Neuropsychopharmacol, 2006, 16, suppl 5, S633-S638. MJ Millan et al. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-HT2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J. Pharmacol. Exp. Ther. 2003, 306 (3), 954–954. Certificate of Analysis Material Safety Data Sheet CNS 5-HT2C MT2 A9 MT1 Melatonin agonist; 5-HT2C antagonist Chemical name N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide Parent CAS No. [138112-76-2] Order Size Unit Price Stock 10 mg €75.00 In Stock

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

Agomelatine

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1492

CAS [138112-76-2]

MF C15H17NO2
MW 243.30

Purity: 99%
Soluble in DMSO

Agomelatine

Description

Potent melatonin agonist; first melatonin antidepressant; also known as a norepinephrine dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor

SA Montgomery. Major depressive disorders: clinical efficacy and tolerability of agomelatine, a new melatonergic agonist. Eur. Neuropsychopharmacol, 2006, 16, suppl 5, S633-S638.

MJ Millan et al. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-HT2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J. Pharmacol. Exp. Ther. 2003, 306 (3), 954–954.

Melatonin agonist; 5-HT2C antagonist

Chemical name

N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

Parent CAS No.

[138112-76-2]

产品资料