产品名称

GMC 1-109

产品货号

Axon 1289 CAS [183140-96-7] MF C19H19F3N4O3SMW 440.44 Purity: 98% Soluble in 0.1N HCl(aq) and DMSO Description Analogue of clozapine (Axon 1146); devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity (IC50 value of 35 nM). KEYWORDS: GMC 1-109 | supplier | Clozapine analog | GMC1-109 | GMC1109 | CAS [183140-96-7] | Axon Medchem | Axon 1289 | Acetylcholine | CHRM1 | Antagonist | Receptors | Muscarinic

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

GMC 1-109

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 1289

CAS [183140-96-7]

MF C19H19F3N4O3S
MW 440.44

Purity: 98%
Soluble in 0.1N HCl(aq) and DMSO

GMC 1-109

Description

Analogue of clozapine (Axon 1146); devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity (IC50 value of 35 nM).

KEYWORDS: GMC 1-109 | supplier | Clozapine analog | GMC1-109 | GMC1109 | CAS [183140-96-7] | Axon Medchem | Axon 1289 | Acetylcholine | CHRM1 | Antagonist | Receptors | Muscarinic

Y Liao et al. Synthesis and pharmacological evaluation of triflate-substituted analogues of clozapine: identification of a novel atypical neuroleptic. J Med Chem. 1997 Dec 5;40(25):4146-53.

Y Liao et al. New (sulfonyloxy)piperazinyldibenzazepines as potential atypical antipsychotics: chemistry and pharmacological evaluation. J Med Chem. 1999 Jun 17;42(12):2235-44.

CNS CHRM1 A18

Clozapine analog devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity

Chemical name

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-yl trifluoromethanesulfonate

Parent CAS No.

[183140-96-7]

产品资料