| 产品名称 | Eplivanserin - SR 46349B |
| 产品货号 | Axon 1439 CAS [130580-02-8] MF C19H21FN2O2.½C4H4O4MW 386.42 Purity: 99% Soluble in DMSO Description Potent, selective and p.o. active 5-HT2A antagonist; functionally also an inverse agonist of 5-HT2A receptor; no affinity to dopamine, histamine and adrenergic receptors; therapeutic agent for the treatment of insomnia References Certificates Categories Extra info M. Rinaldi-Carmona et al. Biochemical and Pharmacological Properties of SR 46349B, a New Potent and Selective 5-Hydroxytryptamine2 Receptor Antagonist. JPET 1992, 262(2), 759-768. F Chaouloff et al. Repeated DOI and SR 46349B treatments do not affect elevated plus-maze anxiety despite opposite effects on cortical 5-HT2A receptors. Eur. J. Pharmacol. 1997, 334(1), 25-29. BR Teergarden et al. 5-HT2A Inverse-Agonists for the Treatment of Insomnia. Current Topics Med. Chem. 2008, 8(11), 969–976. Certificate of Analysis Material Safety Data Sheet CNS 5-HT2A A17 5-HT2A antagonist/inverse agonist Chemical name (E)-1-(2-Fluoro-phenyl)-3-(4-hydroxy-phenyl)-propenone O-(2-dimethylamino-ethyl)-oxime hemi-fumarate Parent CAS No. [130579-75-8] Order Size Unit Price Stock 5 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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Eplivanserin - SR 46349BAxon 1439 CAS [130580-02-8] MF C19H21FN2O2.½C4H4O4
Description
Potent, selective and p.o. active 5-HT2A antagonist; functionally also an inverse agonist of 5-HT2A receptor; no affinity to dopamine, histamine and adrenergic receptors; therapeutic agent for the treatment of insomnia
5-HT2A antagonist/inverse agonist
Chemical name(E)-1-(2-Fluoro-phenyl)-3-(4-hydroxy-phenyl)-propenone O-(2-dimethylamino-ethyl)-oxime hemi-fumarate Parent CAS No.[130579-75-8] |
| 产品资料 |
