产品名称

MDL 105725, (+)- - MDL 105725

产品货号

Axon 1107 CAS [189192-18-5] MF C21H26FNO3MW 359.43 Purity: 99% Optical purity: 98% ee Soluble in DMSO Description Active metabolite of MDL 100907 (Axon 1104), a selective 5-HT2A antagonist; Precursor for [11C]MDL100907 References Certificates Categories Extra info T Ullrich and KC Rice. A practical synthesis of the serotonin 5-HT2a receptor antagonist mdl 100907, its enantiomer and their 3-phenolic derivatives as precursors for [11c]labeled pet ligands. Bioorg. Med. Chem. 2000, 8(10), 2427-2432. J H Kehne et al. Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats.Neuropsychopharmacol. 1996, 15, 116-124. Y Huang et al. An efficient synthesis of the precursors of [11C]MDL100907 labeled in two specific positions. J. Labelled Compd. Radiopharm. 1999, 42, 949-957. DO Scott and TG Heath. Investigation of the CNS penetration of a potent 5-HT2A receptor antagonist (MDL 100,907) and an active metabolite (MDL 105,725) using in vivo microdialysis sampling in the rat. J. Pharm. Biomed Anal. 1998, 17(1), 17-25. Certificate of Analysis Material Safety Data Sheet CNS 5-HT2A A17 5-HT2A antagonist Chemical name 3-((R)-{1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenol Parent CAS No. [189192-18-5] Order Size Unit Price Stock 1 mg €85.00 In Stock

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

MDL 105725, (+)- - MDL 105725

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1107

CAS [189192-18-5]

MF C21H26FNO3
MW 359.43

Purity: 99%
Optical purity: 98% ee
Soluble in DMSO

MDL 105725, (+)-

Description

Active metabolite of MDL 100907 (Axon 1104), a selective 5-HT2A antagonist; Precursor for [¹¹C]MDL100907

T Ullrich and KC Rice. A practical synthesis of the serotonin 5-HT2a receptor antagonist mdl 100907, its enantiomer and their 3-phenolic derivatives as precursors for [11c]labeled pet ligands. Bioorg. Med. Chem. 2000, 8(10), 2427-2432.

J H Kehne et al. Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats.Neuropsychopharmacol. 1996, 15, 116-124.

Y Huang et al. An efficient synthesis of the precursors of [11C]MDL100907 labeled in two specific positions. J. Labelled Compd. Radiopharm. 1999, 42, 949-957.

DO Scott and TG Heath. Investigation of the CNS penetration of a potent 5-HT2A receptor antagonist (MDL 100,907) and an active metabolite (MDL 105,725) using in vivo microdialysis sampling in the rat. J. Pharm. Biomed Anal. 1998, 17(1), 17-25.

CNS 5-HT2A A17

5-HT2A antagonist

Chemical name

3-((R)-{1-[2-(4-Fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenol

Parent CAS No.

[189192-18-5]

产品资料