产品名称

RO 60-0175

产品货号

Axon 1118 CAS [169675-09-6] MF C11H12ClFN2.C4H4O4MW 342.75 Purity: 99% Optical purity: >98% ee Soluble in DMSO Description Putative 5-HT2C agonist; selectivity on 2C is under argument References Certificates Categories Extra info Damjanoska et al. Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol-l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine2C receptor agonist. J. Pharmacol. Exp. Ther. 2003, 304,1209. Kennett et al. Effects of Ro 60-0175, a 5-HT2C receptor agonist, in three animal models of anxiety. Eur. J. Pharmacol. 2000, 387, 197. Martin et al. 5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential. J. Pharmacol. Exp. Ther. 1998, 286, 913. Certificate of Analysis Material Safety Data Sheet CNS 5-HT2C A17 5-HT2C agonist Chemical name (S)-2-(6-Chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine fumarate Parent CAS No. [169675-08-5] Order Size Unit Price Stock 10 mg €115.00 In Stock

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axonmedchem

产品概述

产品详情

RO 60-0175

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1118

CAS [169675-09-6]

MF C11H12ClFN2.C4H4O4
MW 342.75

Purity: 99%
Optical purity: >98% ee
Soluble in DMSO

RO 60-0175

Description

Putative 5-HT2C agonist; selectivity on 2C is under argument

Damjanoska et al. Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol-l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine2C receptor agonist. J. Pharmacol. Exp. Ther. 2003, 304,1209.

Kennett et al. Effects of Ro 60-0175, a 5-HT2C receptor agonist, in three animal models of anxiety. Eur. J. Pharmacol. 2000, 387, 197.

Martin et al. 5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential. J. Pharmacol. Exp. Ther. 1998, 286, 913.

CNS 5-HT2C A17

5-HT2C agonist

Chemical name

(S)-2-(6-Chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine fumarate

Parent CAS No.

[169675-08-5]

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