产品名称 | Fluphenazine decanoate dihydrochloride - Prolixin Decanoate dihydrochloride |
产品货号 | Axon 2127 CAS [2376-65-0] MF C32H44F3N3O2S.2HClMW 664.69 Purity: 99% Soluble in DMSO Description Fluphenazine (available after slow hydrolysis in vivo of the parent molecule) is a potent antipsychotic (Ki values 0.2 nM, 0.11 nM, and 2.0nM for D2, D3, and 5-HT2 receptors, respectively). Fluphenazine exhibits considerable affintiy for 5-HT6 and 5-HT7 receptors (Ki values 15.8nM and 7.9 nM, respectively) as well. References Certificates Categories Extra info H.L. Yale et al. Esters of 4-{3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl}-1-piperazineëthanol as long-acting tranquilizing agents. Synthesis of... J. Med. Chem., 1963, 6, 347-350. P. Seeman et al. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol. Psychiatry. 1998, 3, 123-134. B.L. Roth et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 1994, 268, 1403-1410. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation Endocrinology D2 D3 A17 Antipsychotic with high affinity for dopamine and serotonin receptors Chemical name 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl decanoate dihydrochloride Parent CAS No. [5002-47-1] Order Size Unit Price Stock 10 mg €75.00 In Stock |
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产品品牌 | axonmedchem |
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Fluphenazine decanoate dihydrochloride - Prolixin Decanoate dihydrochlorideAxon 2127 CAS [2376-65-0] MF C32H44F3N3O2S.2HCl
Description
Fluphenazine (available after slow hydrolysis in vivo of the parent molecule) is a potent antipsychotic (Ki values 0.2 nM, 0.11 nM, and 2.0nM for D2, D3, and 5-HT2 receptors, respectively). Fluphenazine exhibits considerable affintiy for 5-HT6 and 5-HT7 receptors (Ki values 15.8nM and 7.9 nM, respectively) as well.
Antipsychotic with high affinity for dopamine and serotonin receptors
Chemical name2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl decanoate dihydrochloride Parent CAS No.[5002-47-1] |
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