产品名称 PNU 22394 hydrochloride
产品货号 Axon 1247 CAS [15923-42-9] MF C13H16N2.HClMW 236.74 Purity: 99% Soluble in DMSO Description Potent 5-HT2 ligand (Ki values 18 nM, 18 nM, and 66 nM for 5-HT2A, 5-HT2C, and 5-HT2B, respectively). PNU 22394 is virtually a full agonist at 5-HT2C receptors (87% of 5-HT), but a partial agonist at 5-HT2A (65% of 5-HT), and 5-HT2B (<15% of 5-HT) receptors, and produced a dose-related decrease in food consumption compared to saline-treated control rats. KEYWORDS: PNU 22394 hydrochloride | supplier | 5-HT2C agonist | PNU22394 | PNU 22394A | CAS [15923-42-9] | [15923-78-1] | Serotonin | 5-HT2C | Agonist | 5-HT2A | 5-HT2B | food | consumption | obesity | weight loss | metabolism | hypophagic | anorexogenic
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PNU 22394 hydrochloride

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1247

CAS [15923-42-9]

MF C13H16N2.HCl
MW 236.74

  • Purity: 99%
  • Soluble in DMSO

PNU 22394 hydrochloride

Description

Potent 5-HT2 ligand (Ki values 18 nM, 18 nM, and 66 nM for 5-HT2A, 5-HT2C, and 5-HT2B, respectively). PNU 22394 is virtually a full agonist at 5-HT2C receptors (87% of 5-HT), but a partial agonist at 5-HT2A (65% of 5-HT), and 5-HT2B (<15% of 5-HT) receptors, and produced a dose-related decrease in food consumption compared to saline-treated control rats.

KEYWORDS: PNU 22394 hydrochloride | supplier | 5-HT2C agonist | PNU22394 | PNU 22394A | CAS [15923-42-9] | [15923-78-1] | Serotonin | 5-HT2C | Agonist | 5-HT2A | 5-HT2B | food | consumption | obesity | weight loss | metabolism | hypophagic | anorexogenic

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