| 产品名称 | Hydroxybuspirone hydrochloride, 6- - BMS 528215 hydrochloride | 6OHB | 6-OH-Bu |
| 产品货号 | Axon 1996 CAS [N.A.] MF C21H31N5O3.HClMW 437.96 Purity: 98% Soluble in water and DMSO Description A major active metabolite of Buspirone (Axon 1995), a 5-HT1A partial agonist; with improved bioavailability (19%) compared with that for buspirone (1.4%); contributes significantly to the clinical efficacy of buspirone as an anxiolytic agent References Certificates Categories Extra info H Wong et al. 6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats. Drug Metab. Dispos. 2007, 35(8), 1387-1392. RC Dockens et al. Pharmacokinetics of 6-hydroxybuspirone and its enantiomers administered individually or following buspirone administration in humans. Biopharm. Drug Dispos. 2007, 28(7), 393-402. SJ Nicholson et al. Development of oral extended release formulations of 6-hydroxybuspirone. Biopharm. Drug Dispos. 2012, 33(9), 522-535. Certificate of Analysis Material Safety Data Sheet CNS 5-HT1A A19 5-HT1A partial agonist Chemical name 6-hydroxy-8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride Parent CAS No. [125481-61-0] Order Size Unit Price Stock 5 mg €135.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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| 产品详情 |
Hydroxybuspirone hydrochloride, 6- - BMS 528215 hydrochloride | 6OHB | 6-OH-BuAxon 1996 CAS [N.A.] MF C21H31N5O3.HCl
DescriptionA major active metabolite of Buspirone (Axon 1995), a 5-HT1A partial agonist; with improved bioavailability (19%) compared with that for buspirone (1.4%); contributes significantly to the clinical efficacy of buspirone as an anxiolytic agent
5-HT1A partial agonist
Chemical name6-hydroxy-8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride Parent CAS No.[125481-61-0] |
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