产品名称 | GW 803430 - GW 3430 |
产品货号 | Axon 1569 CAS [515141-51-2] MF C25H24ClN3O3SMW 481.99 Purity: 98% Soluble in DMSO Description Selective, non-peptide antagonist at the melanin concentrating hormone receptor 1 (MCH1 aka MCH R1). In animal studies it has anxiolytic, antidepressant and anorectic effects References Certificates Categories Extra info DR Gehlert et al. Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression. J. Pharmacol. Exp. Ther. 2009, 329 (2), 429–438. SL Able et al. Localisation of melanin-concentrating hormone receptor 1 in rat brain and evidence that sleep parameters are not altered despite high central receptor occupancy. Eur. J. Pharmacol. 2009, 616(1-3), 101-106. S Chaki and K Kanuma. Neuropeptide receptors: Novel therapeutic targets for depression and anxiety disorders. Drugs Fut. 2007, 32(9), 809. Certificate of Analysis Material Safety Data Sheet CNS MCH1 Endocrinology A5 MCH1 antagonist Chemical name 6-(4-Chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one Parent CAS No. [515141-51-2] Order Size Unit Price Stock 5 mg €85.00 In Stock |
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产品品牌 | axonmedchem |
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GW 803430 - GW 3430Axon 1569 CAS [515141-51-2] MF C25H24ClN3O3S
Description
Selective, non-peptide antagonist at the melanin concentrating hormone receptor 1 (MCH1 aka MCH R1). In animal studies it has anxiolytic, antidepressant and anorectic effects
MCH1 antagonist
Chemical name6-(4-Chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one Parent CAS No.[515141-51-2] |
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