产品名称

INK 128

产品货号

Axon 2142 CAS [1224844-38-5] MF C15H15N7OMW 309.33 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective mTOR inhibitor. KEYWORDS: INK 128 | supplier | mTOR inhibitor | MLN 0128 | Sapanisertib | INK128 | MLN0128 | CAS [1224844-38-5] | Phosphatidylinositol | mTOR | Inhibitor

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

INK 128

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2142

CAS [1224844-38-5]

MF C15H15N7O
MW 309.33

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

INK 128

Description

Potent and selective mTOR inhibitor.

KEYWORDS: INK 128 | supplier | mTOR inhibitor | MLN 0128 | Sapanisertib | INK128 | MLN0128 | CAS [1224844-38-5] | Phosphatidylinositol | mTOR | Inhibitor

AC Hsieh, Y Liu et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature 2012, 485, 55–61.

K Jessen et al. Abstract B148: INK128 is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. Mol. Cancer Ther. 2009, 8(12), S1.

MR Janes et al. Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia. Leukemia. 2013, 27(3), 586-594.

Cell Signaling & Oncology mTOR PI3K-Akt-mTOR EC 2.7.11.1

Potent and selective mTOR inhibitor

Chemical name

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine

Parent CAS No.

[1224844-38-5]

产品资料