| 产品名称 | PF 04691502 |
| 产品货号 | Axon 1855 CAS [1013101-36-4] MF C22H27N5O4MW 425.48 Purity: 99% Soluble in DMSO Description Potent, selective, oral and ATP-competitive inhibitor of class I PI3K (Ki: 1-2 nM) and mTOR kinases (Ki: 16 nM); it inhibits PI3K/mTOR signaling and induces cell cycle arrest in cancer cells References Certificates Categories Extra info J Yuan et al. PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activity. Mol. Cancer Ther. 2011, 10, 2189. H Cheng et al. Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design. Med. Chem. Commun. 2010, 1, 139-144. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology PI3K mTOR PI3K-Akt-mTOR EC 2.7.11.1 Pfizer Licensed Products PI3K and mTOR tyrosine kinase inhibitor Chemical name 2-amino-8-((1r,4r)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [1013101-36-4] Order Size Unit Price Stock 5 mg €90.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
PF 04691502Axon 1855 CAS [1013101-36-4] MF C22H27N5O4
Description
Potent, selective, oral and ATP-competitive inhibitor of class I PI3K (Ki: 1-2 nM) and mTOR kinases (Ki: 16 nM); it inhibits PI3K/mTOR signaling and induces cell cycle arrest in cancer cells
PI3K and mTOR tyrosine kinase inhibitor
Chemical name2-amino-8-((1r,4r)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[1013101-36-4] |
| 产品资料 |
