| 产品名称 | Palomid 529 - SG 00529 |
| 产品货号 | Axon 1718 CAS [914913-88-5] MF C24H22O6MW 406.43 Purity: 98% Soluble in DMSO Description Small molecule tyrosine kinase inhibitor, targeting Akt/mTOR; Dual TORC1/2 inhibitor of the PI3K/Akt//mTOR pathway having broad activity in angiogenesis and cellular proliferation; P529 inhibits cell growth of a broad spectrum of cancer cell lines References Certificates Categories Extra info Q Xue et al. Palomid 529, a Novel Small-Molecule Drug, Is a TORC1/TORC2 Inhibitor That Reduces Tumor Growth, Tumor Angiogenesis, and Vascular Permeability. Cancer Res. 2008, 68(22), 9551-9557. R Diaz et al. The novel Akt inhibitor Palomid 529 (P529) enhances the effect of radiotherapy in prostate cancer. Br. J. Cancer 2009, 100, 932–940. GL Gravina et al. The TORC1/TORC2 inhibitor, Palomid 529, reduces tumor growth and sensitizes to docetaxel and cisplatin in aggressive and hormone-refractory prostate cancer cells. Endocr. Relat. Cancer. 2011, 18(4), 385-400. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology mTOR PI3K-Akt-mTOR EC 2.7.11.1 mTOR inhibitor Chemical name 8-(1-hydroxyethyl)-2-methoxy-3-(4-methoxybenzyloxy)-6H-benzo[c]chromen-6-one Parent CAS No. [914913-88-5] Order Size Unit Price Stock 5 mg €90.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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Palomid 529 - SG 00529Axon 1718 CAS [914913-88-5] MF C24H22O6
Description
Small molecule tyrosine kinase inhibitor, targeting Akt/mTOR; Dual TORC1/2 inhibitor of the PI3K/Akt//mTOR pathway having broad activity in angiogenesis and cellular proliferation; P529 inhibits cell growth of a broad spectrum of cancer cell lines
mTOR inhibitor
Chemical name8-(1-hydroxyethyl)-2-methoxy-3-(4-methoxybenzyloxy)-6H-benzo[c]chromen-6-one Parent CAS No.[914913-88-5] |
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