产品名称

Prucalopride

产品货号

Axon 1479 CAS [179474-81-8] MF C18H26ClN3O3MW 367.87 Purity: 99% Soluble in DMSO Description Selective 5-HT4 receptor agonist; a gastroprokinetic agent for the treatment of constipation and irritable bowel syndrome; showed memory-enhancing effects in mice through modulation of cholinergic pathways; hence an indication of potential as Alzheimer's disease therapy References Certificates Categories Extra info EP Bouras et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999, 44(5), 682-6. JH De Maeyer et al. 5-HT4 receptor agonists: similar but not the same. Neurogastroenterol. Motility. 2008, 20(2), 99-112. J Tack et al. Prucalopride (resolor(R)) in the treatment of severe chronic constipation in patients dissatisfied with laxatives. Gut. 2009, 58(3), 357-65. M Cachard-Chastel et al. Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice. Behav. Brain Res. 2008, 187(2), 455-61. Certificate of Analysis Material Safety Data Sheet CNS 5-HT4 A19 5-HT4 agonist Chemical name 4-Amino-5+K445-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide Parent CAS No. [179474-81-8] Order Size Unit Price Stock 10 mg €90.00 In Stock

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

Prucalopride

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1479

CAS [179474-81-8]

MF C18H26ClN3O3
MW 367.87

Purity: 99%
Soluble in DMSO

Prucalopride

Description

Selective 5-HT4 receptor agonist; a gastroprokinetic agent for the treatment of constipation and irritable bowel syndrome; showed memory-enhancing effects in mice through modulation of cholinergic pathways; hence an indication of potential as Alzheimer's disease therapy

EP Bouras et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999, 44(5), 682-6.

JH De Maeyer et al. 5-HT4 receptor agonists: similar but not the same. Neurogastroenterol. Motility. 2008, 20(2), 99-112.

J Tack et al. Prucalopride (resolor(R)) in the treatment of severe chronic constipation in patients dissatisfied with laxatives. Gut. 2009, 58(3), 357-65.

M Cachard-Chastel et al. Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice. Behav. Brain Res. 2008, 187(2), 455-61.

CNS 5-HT4 A19

5-HT4 agonist

Chemical name

4-Amino-5+K445-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide

Parent CAS No.

[179474-81-8]

产品资料