产品名称 Stem Cell 4i inhibitor Set - iPSC-TSPC inhibitor Set
产品货号 Axon 5009 CAS [N.A.] MF #N/AMW #N/A Purity: 99% Soluble in DMSO Description A convenient set of four small molecule pathway inhibitors, ROCK inhibitor Thiazovivin (Axon 1535), TGF-β inhibitor SB 431542 (Axon 1661), MEK inhibitor PD 0325901 (Axon 1408) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (termed as stem cell 4i or iPSC-TSPC). The small molecule cocktail of 4 inhibitors (SMC4) was reported to efficiently generate, characterize and maintain single cell and feeder-free (FF) cultural human induced pluripotent stem cells (iPSCs, or hiPSCs), hence a high-throughput reprogramming platform. Read more: Additional Product Information Show all Axon Ligand™ Sets References Certificates Categories Extra info S.M. Chambers et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature Biotechnol. 2012, 30, 715-720.   List of publications using PD 0325901 (Axon 1408) purchased from Axon Medchem  List of publications using CHIR 99021 (Axon 1386) purchased from Axon Medchem Certificate of Analysis Material Safety Data Sheet Additional Product Information Apoptosis Cell Signaling & Oncology CNS Diabetes & Metabolism Immunology Pain & Inflammation Stem Cell GSK-3 ROCK Wnt-β-Catenin TGF-β MAPK PI3K-Akt-mTOR Stem Cells MEK TGF-βR Pfizer Licensed Products Set of Thiazovivin, SB 431542, PD 0325901, and CHIR 99021 (inhibitors of ROCK, TGF-β, MEK, and GSK-3 resp.) Chemical name N.A. Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [N.A.] Order Size Unit Price Stock Each 2 mg €190.00 In Stock
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Stem Cell 4i inhibitor Set - iPSC-TSPC inhibitor Set

Based on 18 reference(s) in Google Scholar 10 10 18

Axon 5009

CAS [N.A.]

MF #N/A
MW #N/A

  • Purity: 99%
  • Soluble in DMSO

Stem Cell 4i inhibitor Set

Description

A convenient set of four small molecule pathway inhibitors, ROCK inhibitor Thiazovivin (Axon 1535), TGF-β inhibitor SB 431542 (Axon 1661), MEK inhibitor PD 0325901 (Axon 1408) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (termed as stem cell 4i or iPSC-TSPC). The small molecule cocktail of 4 inhibitors (SMC4) was reported to efficiently generate, characterize and maintain single cell and feeder-free (FF) cultural human induced pluripotent stem cells (iPSCs, or hiPSCs), hence a high-throughput reprogramming platform.

Read more: Additional Product Information

Show all Axon Ligand™ Sets

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