产品名称 | Stem Cell 4i inhibitor Set - iPSC-TSPC inhibitor Set | |
产品货号 | Axon 5009 CAS [N.A.] MF #N/AMW #N/A Purity: 99% Soluble in DMSO Description A convenient set of four small molecule pathway inhibitors, ROCK inhibitor Thiazovivin (Axon 1535), TGF-β inhibitor SB 431542 (Axon 1661), MEK inhibitor PD 0325901 (Axon 1408) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (termed as stem cell 4i or iPSC-TSPC). The small molecule cocktail of 4 inhibitors (SMC4) was reported to efficiently generate, characterize and maintain single cell and feeder-free (FF) cultural human induced pluripotent stem cells (iPSCs, or hiPSCs), hence a high-throughput reprogramming platform. Read more: Additional Product Information Show all Axon Ligand™ Sets References Certificates Categories Extra info S.M. Chambers et al. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature Biotechnol. 2012, 30, 715-720. List of publications using PD 0325901 (Axon 1408) purchased from Axon Medchem List of publications using CHIR 99021 (Axon 1386) purchased from Axon Medchem Certificate of Analysis Material Safety Data Sheet Additional Product Information Apoptosis Cell Signaling & Oncology CNS Diabetes & Metabolism Immunology Pain & Inflammation Stem Cell GSK-3 ROCK Wnt-β-Catenin TGF-β MAPK PI3K-Akt-mTOR Stem Cells MEK TGF-βR Pfizer Licensed Products Set of Thiazovivin, SB 431542, PD 0325901, and CHIR 99021 (inhibitors of ROCK, TGF-β, MEK, and GSK-3 resp.) Chemical name N.A. Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [N.A.] Order Size Unit Price Stock Each 2 mg €190.00 In Stock | |
产品价格 | 现货询价,电话:010-67529703 | |
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产品品牌 | axonmedchem | |
产品概述 | ||
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Stem Cell 4i inhibitor Set - iPSC-TSPC inhibitor SetAxon 5009 CAS [N.A.] MF #N/A
DescriptionA convenient set of four small molecule pathway inhibitors, ROCK inhibitor Thiazovivin (Axon 1535), TGF-β inhibitor SB 431542 (Axon 1661), MEK inhibitor PD 0325901 (Axon 1408) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (termed as stem cell 4i or iPSC-TSPC). The small molecule cocktail of 4 inhibitors (SMC4) was reported to efficiently generate, characterize and maintain single cell and feeder-free (FF) cultural human induced pluripotent stem cells (iPSCs, or hiPSCs), hence a high-throughput reprogramming platform. Read more: Additional Product Information Show all Axon Ligand™ Sets
List of publications using PD 0325901 (Axon 1408) purchased from Axon Medchem List of publications using CHIR 99021 (Axon 1386) purchased from Axon Medchem
Set of Thiazovivin, SB 431542, PD 0325901, and CHIR 99021 (inhibitors of ROCK, TGF-β, MEK, and GSK-3 resp.)
Chemical nameN.A. Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[N.A.] |
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