Phospho-Aurora Kinase (Thr288) Antibody detects endogenous levels of Aurora Kinase only when phosphorylated at Threonine 288. The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression.
| Target |
Aurora Kinase (pT288) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
O14965
|
| GeneID |
6790
|
| Gene Symbol |
AURKA |
| OMIM |
603072
|
| Enzyme Commission Number |
EC 2.7.11.1 |
| HGNC |
11393 |
| Ensembl |
ENSG00000087586 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |