Phospho-IKK beta (Tyr188) Antibody detects endogenous levels of IKK beta only when phosphorylated at Tyrosine 188. IKK-beta is a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.
| Target |
IKK beta (pY188) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
O14920
|
| GeneID |
3551
|
| Gene Symbol |
IKBKB |
| OMIM |
603258
|
| Enzyme Commission Number |
EC 2.7.11.10 |
| HGNC |
5960 |
| Ensembl |
ENSG00000104365 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |