Sequence: H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
CAS-No.: 217082-58-1
Mol.weight: 1550.85
SumFormula: C₆₉H₁₁₁N₂₃O₁₆S
Bulk item no.: H-4566
Synonym(s):
EINECS no.: -
MDL no.: MFCD02094627

Review:

Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.