产品详情 |
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Antigenic Specificity | Fc epsilon RI alpha |
Clone | MAR-1 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | PE-Dazzle™ 594 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Dazzle™ 594 anti-mouse FcεRIα. FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit. |
Immunogen | n/a |
Other Names | FceRIa, FceRI-α, high affinity IgE receptor |
Gene, Accession # | Gene ID: 2205 |
Catalog # | 134332 |
Price | |
Order / More Info | Fc epsilon RI alpha Antibody from BIOLEGEND |
Product Specific References | n/a |
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