| 产品详情 |
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| Antigenic Specificity | Fc epsilon RI alpha |
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| Clone | AER-37 (CRA-1) |
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| Host Species | Mouse |
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| Reactive Species | human, baboon, cynomolgus, rhesus |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Western Blot (WB), Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human FcεRIα. High affinity IgE receptor (FcεRI) plays a key role in IgE-mediated allergic immune response. FcεRI is a tetrameric receptor complex, which is composed of one α-subunit (FcεRIα), one β-subunit, and two γ-subunits. FcεRIα directly binds IgE with high affinity, while the β- and γ-chains are responsible for mediating intracellular signals. FcεRIα is a 50 kD transmembrane protein with Ig superfamily structure. It is primarily found on mast cells and basophils. Further studies have indicated that FcεRIα is also expressed on many inflammatory cells including cutaneuos Langerhans cells, dendritic cells, monocytes of patients with allergic disorders, platelets, bronchial epithelial cells, eosinophils produced in hypereosinophilic syndrome, and neutrophils from allergy-induced asthma patients. |
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| Immunogen | n/a |
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| Other Names | FceRIa, FceRI-a, FceRI-alpha, FceRI alpha, high affinity IgE receptor |
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| Gene, Accession # | Gene ID: 2205 |
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| Catalog # | 334602 |
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| Price | |
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| Order / More Info | Fc epsilon RI alpha Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20512127 |
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| 产品资料 |
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