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| Product Name | Activated Protein C (APC) Inhibitor Screening Kit (Colorimetric) |
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| Description | Activated protein C (APC) (3.4.21.69), a Vitamin K dependent serine protease, is formed by activation of Protein C by Thrombomodulin bound on the surface of endothelial cells. By degrading coagulation factors Va and VIIIa, APC inhibits blood coagulation which helps in the prevention of thrombosis. Blood coagulation can be stimulated by inhibition of APC. Thus, APC inhibitors play an important role in the treatment of disease like Haemophilia. BioVision's APC Inhibitor Screening Kit can be used to screen for potent inhibitors of APC activity. It utilizes the proteolytic activity of an active APC on a peptide substrate which releases a colored product. The released product can be easily quantified using an absorbance microplate reader. In the |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | Screening of drugs and novel ligands for interaction with human recombinant Activated Protein C |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K427-100 |
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| Order / More Info | Activated Protein C (APC) Inhibitor Screening Kit (Colorimetric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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