| 产品详情 |
| Edit |   |
|---|
| Product Name | PLX7904 |
|---|
| Description | A RAF inhibitor (IC50s = 2.4, 140, and 91 nM for mutant B-RAFV600E, wild-type B-RAF, and C-RAF, respectively); inhibits phosphorylation of ERK in A375 and COLO 829 cells (IC50s = 16 and 18 nM, respectively); does not induce paradoxical pERK activation and proliferation of cancer cell lines (EC50s = >200 µM); inhibits tumor growth in a mouse COLO 205 colon cancer xenograft model , |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | PLX-7904 4032 BRAF V600E CRAF A-375 BAY-439006 BAY439006 COLO829 COLO205 |
|---|
| Gene, Accession, CAS # | CAS: 1393465-84-3 |
|---|
| Catalog # | 20710-10 |
|---|
| Price | |
|---|
| Order / More Info | PLX7904 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|