| 产品详情 |
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| Product Name | PLX7904 |
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| Description | A RAF inhibitor (IC50s = 2.4, 140, and 91 nM for mutant B-RAFV600E, wild-type B-RAF, and C-RAF, respectively); inhibits phosphorylation of ERK in A375 and COLO 829 cells (IC50s = 16 and 18 nM, respectively); does not induce paradoxical pERK activation and proliferation of cancer cell lines (EC50s = >200 µM); inhibits tumor growth in a mouse COLO 205 colon cancer xenograft model , |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PLX-7904 4032 BRAF V600E CRAF A-375 BAY-439006 BAY439006 COLO829 COLO205 |
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| Gene, Accession, CAS # | CAS: 1393465-84-3 |
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| Catalog # | 20710-25 |
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| Price | |
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| Order / More Info | PLX7904 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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