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| Product Name | Recombinant Echis carinatus Disintegrin EC3B |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 23.4kDa. Full Length: 1-67aa. N-terminal 6xHis-SUMO-tagged. Echis carinatus (Saw-scaled viper). Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | UniProt: P81631 |
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| Catalog # | RPC22336 |
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| Order / More Info | Recombinant Echis carinatus Disintegrin EC3B from BIOMATIK |
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| Product Specific References | n/a |
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