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| Product Name | Recombinant Rat Basic leucine zipper transcriptional factor ATF-like 3 (Batf3) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 17.1kDa. Full Length: 1-133aa. N-terminal 6xHis-tagged. Rattus norvegicus (Rat). AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune syst. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. Required for development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Jun dimerization protein 1; JDP-1 |
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| Gene, Accession, CAS # | Batf3, UniProt: P97876 |
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| Catalog # | RPC24524 |
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| Order / More Info | Recombinant Rat Basic leucine zipper transcriptional factor ATF-like 3 (Batf3) from BIOMATIK |
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| Product Specific References | n/a |
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