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Product Name | Recombinant Escherichia coli Elongation factor P (efp) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 22.5kDa. Full Length of Mature Protein: 2-188aa. N-terminal 6xHis-tagged. Escherichia coli (strain K12). Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Beta-lysylation at Lys-34 is required for alleviation. The Pro codons and their context do not affect activity; only consecutive Pro residues (not another amino acid) are affected by EF-P. Has stimulatory effects on peptide bond formation between ribosome-bound initiator tRNA (fMet) and puromycin, and N-acetyl-Phe tRNA (Phe)-primed poly (U)-directed poly (Phe) synthesis. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Short name:EF-P |
Gene, Accession, CAS # | efp, UniProt: P0A6N4 |
Catalog # | RPC25245 |
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Order / More Info | Recombinant Escherichia coli Elongation factor P (efp) from BIOMATIK |
Product Specific References | n/a |
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