| 产品详情 |
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| Product Name | Recombinant Human Interleukin-8 protein (CXCL8) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 38.31kDa. Partial: 31-370aa. C-terminal 6xHis-tagged. Homo sapiens (Human). Signal Regulatory Protein a (SIRPa) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPa contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPa can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPa acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPa shows adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. SIRPa engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis, mast cell activation and dendritic cell activation |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1; SHP Substrate 1; SHPS-1; Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs; Bit; CD172 Antigen-Like Family Member A; Inhibitory Feceptor SHPS-1; Macrophage Fusion Receptor; MyD-1 Antigen; Signal-Regulatory Protein Alpha-1; Sirp-Alpha-1; Signal-Regulatory Protein Alpha-2; Sirp-Alpha-2; Signal-Regulatory Protein Alpha-3; Sirp-Alpha-3; p84; CD172a; SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP |
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| Gene, Accession, CAS # | SIRPA, UniProt: P78324 |
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| Catalog # | RPC26973 |
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| Order / More Info | Recombinant Human Interleukin-8 protein (CXCL8) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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