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| Product Name | Recombinant Naja kaouthia Cobra venom factor, partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 44.4kDa. Partial: 733-984aa. N-terminal 6xHis-SUMO-tagged. Naja kaouthia (Monocled cobra) (Naja siamensis). Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Complement C3 homolog |
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| Gene, Accession, CAS # | UniProt: Q91132 |
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| Catalog # | RPC20297 |
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| Order / More Info | Recombinant Naja kaouthia Cobra venom factor, partial from BIOMATIK |
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| Product Specific References | n/a |
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