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| Product Name | Recombinant Naja mossambica Snake venom metalloproteinase-disintegrin-like mocarhagin |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 50.7kDa. Full Length of Mature Protein: 192-609aa. N-terminal 6xHis-tagged. Naja mossambica (Mozambique spitting cobra). Snake venom zinc metalloproteinase that inhibits platelet aggregation by cleaving platelet glycoprotein Ib alpha (GP1BA) at Glu-298/Asp-299, and abolishes binding of von Willebrand factor (VWF) to GPIBA. Cleaves P-selectin glycoprotein ligand-1 (PSGL-1/SELPLG) at Tyr-51/Asp-52, and completely abolishes the binding of PSGL-1 to P-selectin. Anionic amino acid sequences containing sulfated tyrosines are needed for cleavages. Inhibits the thrombin-induced platelet aggregation, and the thrombin-induced release of ATP and ADP. Has lectin activity |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Zinc metalloproteinase mocarhagin |
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| Gene, Accession, CAS # | UniProt: Q10749 |
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| Catalog # | RPC22953 |
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| Order / More Info | Recombinant Naja mossambica Snake venom metalloproteinase-disintegrin-like mocarhagin from BIOMATIK |
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| Product Specific References | n/a |
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