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| Product Name | Recombinant Mouse TNF-α (carrier-free) |
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| Description | TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells (principally CD4+), and NK-cells. Many transformed cell lines also secrete TNF-α. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils. |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | BA |
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| Other Names | Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF2 |
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| Gene, Accession, CAS # | Gene ID: 21926 |
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| Catalog # | 575204 |
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| Order / More Info | Recombinant Mouse TNF-α (carrier-free) from BIOLEGEND |
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| Product Specific References | PubMed: 19710421,22219321,22815286 |
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