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Product Name | Homocysteine Assay Kit (Fluorometric) |
Description | Homocysteine is a non-proteogenic amino acid synthesized intracellularly by removal of the N-methyl group from the essential amino acid methionine. Homocysteine is exported from cells into the blood, where it exists mainly as an oxidized disulfide species, either as a dimer or bound to cysteine residues of serum proteins. The reduced form of homocysteine (`free' homocysteine) can be metabolized into cysteine via the transsulfuration pathway; however, it can also undergo intramolecular cyclization, forming the highly reactive pro-oxidant homocysteine thiolactone. Subsequent N-homocysteinylation of protein lysine residues by the reactive thiolactone disrupts protein conformation, leading to formation of cytotoxic protein aggregates. Homocyste |
Size | 100 assays |
Concentration | n/a |
Applications | Estimation of Homocysteine in various biological samples |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | K531-100 |
Price | |
Order / More Info | Homocysteine Assay Kit (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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