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Product Name | RNF7, 1-113aa, Human, His tag, E.coli (Denatured) |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea. RNF7 is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHuK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. Recombinant human RNF7 protein, fused to His-tag at N-terminus, was expressed in E.coli . |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | RING-box protein 2 isoform 1, Ring finger protein 7, CKBBP1, ROC2, SAG |
Gene, Accession, CAS # | NP 055060 |
Catalog # | ATGP2286 |
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Order / More Info | RNF7, 1-113aa, Human, His tag, E.coli (Denatured) from ATGen |
Product Specific References | n/a |
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