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| Product Name | TCEA1, 1-301aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer, pH7.5, 20% glycerol, 1mM DTT, 50mM NaCl . TCEA1 (Transcription elongation factor A protein 1) belongs to the TFS-II family. TCEA1 binds to Pol II and functions to cleave the nascent transcript, thereby unlocking the complex and allowing transcription to continue. Localized to the nucleus, TCEA1 contains three independently-folding domains, all of which are necessary for proper binding to Pol II. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Recombinant human TCEA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Transcription elongation factor A protein 1, GTF2S, SII, TCEA, TF2S, TFIIS |
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| Gene, Accession, CAS # | NP 006747 |
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| Catalog # | ATGP1534 |
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| Order / More Info | TCEA1, 1-301aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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