| 产品详情 |
| Edit |   |
|---|
| Product Name | TCEB1, 1-112aa, Human, His tag E.coli |
|---|
| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.. TCEB1 (elongin C) is a subunit of elongin, which is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template encoded arresting sites. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau(VHL) tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant human TCEB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
|---|
| Size | 0.5mg, 100ug, 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | SDS-PAGE |
|---|
| Other Names | Transcription elongation factor B polypeptide 1, SIII, Elongin-C |
|---|
| Gene, Accession, CAS # | NP 005639 |
|---|
| Catalog # | ATGP1363 |
|---|
| Price | |
|---|
| Order / More Info | TCEB1, 1-112aa, Human, His tag E.coli from ATGen |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|