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Product Name | TDP1, 1-608aa, Human, His-tag, Baculovirus |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. TDP1, also known as tyrosyl-DNA phosphodiesterase 1, is involved in repairing stalled topoisomerase l-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase l and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical meditated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | tyrosyl-DNA phosphodiesterase 1 isoform a, TDP1, Tyrosyl-DNA phosphodiesterase 1, Tyr-DNA phosphodiesterase 1 |
Gene, Accession, CAS # | NP 060789 |
Catalog # | ATGP3593 |
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Order / More Info | TDP1, 1-608aa, Human, His-tag, Baculovirus from ATGen |
Product Specific References | n/a |
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