产品名称 D-2-Hydroxyglutarate (D2HG) Assay Kit (Colorimetric) from BIOVISION, INC.
产品货号 K213-100
产品价格 现货询价,电话:010-67529703
产品规格 100 assays
产品品牌 BIOVISION, INC.
产品概述
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Product NameD-2-Hydroxyglutarate (D2HG) Assay Kit (Colorimetric)
DescriptionIn eukaryotic cells, Isocitrate Dehydrogenase (IDH1, IDH2 and IDH3) catalyzes the interconversion of Isocitrate and α-Ketoglutarate. In human cancers, an IDH mutation causes a gain-of-function, which reduces its affinity for isocitrate and facilitates the conversion of α-ketoglutarate to D-2-Hydroxyglutarate in the presence of NADP. D-2-Hydroxyglutarate (D2HG) is present at low level in normal cells and tissues, but is significantly elevated in metabolic diseases and various cancers. Therefore, detection of elevated D2HG is important for early diagnosis, prognosis and the development of therapeutic strategies against these maladies. BioVision's D-2-Hydroxyglutarate Assay Kit provides a convenient method to detect D2HG in biologi
Size100 assays
Concentrationn/a
Applications• Measurement of D2HG level in various cell/tissues/biological fluids.
Other NamesD2HG assay kit
Gene, Accession, CAS #n/a
Catalog #K213-100
Price
Order / More InfoD-2-Hydroxyglutarate (D2HG) Assay Kit (Colorimetric) from BIOVISION, INC.
Product Specific Referencesn/a
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