产品详情 |
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Antigenic Specificity | EPO |
Clone | M0312E3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-EPO. EPO is the major regulator of differentiation, proliferation, and survival of erythroid progenitors. Hypoxia induces erythropoiesis which causes cells to produce hypoxia inducible factor (HIF) that is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induce EPO production in the kidneys and liver, and mobilize iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with a number of conditions, such as chronic kidney disease, cancer patients on chemotherapy, and antiviral HIV therapy. |
Immunogen | Recombinant human EPO |
Other Names | Erythropoietin, MVCD2, EP, Epoetin |
Gene, Accession # | Gene ID: 2056 |
Catalog # | 662202 |
Price | |
Order / More Info | EPO Antibody from BIOLEGEND |
Product Specific References | n/a |
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