| 产品详情 |
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| Antigenic Specificity | Human IgD |
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| Clone | n/a |
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| Host Species | n/a |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | dextran conjugate |
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| Size | 10 ug |
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| Concentration | 100 ug/ml |
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| Applications | n/a |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Crosslinking membrane IgD on B cells with unconjugated anti-IgD antibody induces B cell proliferation at ug/ml concentrations. By contrast, anti-IgD dextran (anti-IgD dex or anti-delta-dex) induce vigorous B cell proliferation at ng/ml concentrations (Brunswick et al., J. Immunol. 140:3364, 1988). Furthermore, in contrast to unconjugated anti-IgD, anti-IgD-dex-activated B cells undergo substantial Ig class switching and differentiation into Ig-secreting cells in the presence of various second signals, including cytokines and Toll-like receptor ligands (Snapper and Mond, J. Immunol. 157:2229, 1996). Thus, Anti-IgD-dex is an efficient and potent polyclonal B cell activator for studying a wide range of B cell functions. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | FinaBio#0002 |
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| Price | |
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| Order / More Info | Human IgD Antibody from FINA BIOSOLUTIONS LLC |
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| Product Specific References | n/a |
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| 产品资料 |
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