| 产品详情 |
| Edit |   |
|---|
| Product Name | MMP-14, Active, Human Recombinant |
|---|
| Description | The Matrix metalloproteinase-14 (MMP-14) belongs to a family of zinc-dependent endopeptidases. The ability of MMP-14 to degrade type I collagen, and activate pro-MMP-2 and pro-MMP-9 makes it a key enzyme in many physiological and pathological processes such as angiogenesis and tumor invasion. MMP-14 is structurally a multi-domain metalloenzyme, composed of a prodomain, a metal-binding catalytic domain, a hinge region, a hemopexin-like domain, a transmembrane domain, and a cytoplamasic tail. The catalytic, and hinge domains of MT1-MMP were expressed in Escherichia coli and the active form was generated by successive autoproteolysis of the N- and C-terminal sites during refolding. MW: ~ 24.0 kDa (112-318 aa). Purity ≥90% |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | Matrix metalloproteinase-14, MT1-MMP |
|---|
| Gene, Accession, CAS # | MMP14, Gene ID: 4323, Accession: P50281 |
|---|
| Catalog # | 8009-50 |
|---|
| Price | |
|---|
| Order / More Info | MMP-14, Active, Human Recombinant from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|