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| Product Name | IGF-II ELISA |
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| Description | The Eagle Biosciences ELISA for IGF-II is a so-called Sandwich-Assay. It utilizes two specific and high affinity antibodies for this protein. The first antibody, immobilized on the microtiter plate, and the added second biotinylated antibody are binding the IGF-II in the sample. The Streptavidin-Peroxidase Enzyme Conjugate subsequently binds to the complex. In the closing substrate reaction the turn of the colour will be high specific catalysed, quantitatively depending on the IGF-II-level of the samples. Sample Types: serum, plasma, urine, saliva, cell culture. Range: 0.45 - 9 ng/ml. Sensitivity: 0.04 ng/ml. Time: 3 hours • Insulin-like growth factors (IGF) I and II play a pivotal role in regulating the proliferation and differentiation of many cell types (1-3). IGF-I is identical with Somatomedin C (Sm-C) (4) and has a molecular weight of 7649 daltons (5). Its major regulators are growth hormone (GH) and nutrition (6). In contrast to many other peptide hormones, IGFs are avidly bound to specific binding proteins (IGFBP). The seven IGFBPs which are known at present (7,8,22) either bind IGF-I and IGF-II with similar affinities or show a preference for IGF-II (9,10). |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | IGF-II, IGF-2, Insulin Like Growth Factor 2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E30 |
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| Order / More Info | IGF-II ELISA from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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