产品名称 BAY 87-2243 from BIOVISION, INC.
产品货号 B1878-25
产品价格 现货询价,电话:010-67529703
产品规格 25 mg
产品品牌 BIOVISION, INC.
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Product NameBAY 87-2243
DescriptionBAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation. It inhibits HIF-1α and HIF-2α protein accumulation under hypoxic conditions in non-small cell lung cancer (NSCLC) cell line H460 but had no effect on HIF-1α protein levels induced by the hypoxia mimetics desferrioxamine or cobalt chloride. In addition, BAY 87-2243 is also found to act as an inhibitor of mitochondrial function. It can inhibit the oxygen consumption with IC50 value of 10 nM. MW: 525.53. Purity ≥98% by HPLC
Size25 mg
Concentrationn/a
Applicationsn/a
Other Names5-(1-((2-(4-cyclopropylpiperazin-1-yl)pyridin-4-yl)methyl)-5-methyl-1H-pyrazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
Gene, Accession, CAS #CAS: 1227158-85-1
Catalog #B1878-25
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Order / More InfoBAY 87-2243 from BIOVISION, INC.
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