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Product Name | Erastin |
Description | Erastin is a selective antitumor agent that displays greater lethality in human tumour cells harbouring mutations in the oncogenes HRAS, KRAS or BRAF. It binds to mitochondrial volatage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating. Erastin rapidly induces an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling. MW: 547.04. Purity ≥98% by HPLC |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone |
Gene, Accession, CAS # | CAS: 571203-78-6 |
Catalog # | 2231-1 |
Price | |
Order / More Info | Erastin from BIOVISION, INC. |
Product Specific References | n/a |
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