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Product Name | ErbB4/HER4 (His Tagged), Human Recombinant |
Description | ErbB4, also known as Her4, is a member of the tyrosine kinase receptors (RTK) and the epidermal growth factor receptor (EGFR) subfamily, and appears to play important roles in differentiation, development and certain carcinomas. It is a single transmembrane-span type I glycoprotein structurally consisting of multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 (PI-3) kinase binding site and a PDZ domain binding motif. However, the last two domains are absent in one of the two naturally occurring ErbB4 isoforms, ErbB4 CYT-2. ErbB4 ligands include the neuregulins, betacellulin and heparin-binding EGF-like growth factor (HB-EGF). Typically, heterodimerization of ErbB4 with ErbB2 forms the h |
Size | 5 µg |
Concentration | n/a |
Applications | RUO |
Other Names | HER4, MGC138404, p180erbB4, ERBB4 |
Gene, Accession, CAS # | ERBB4, Gene ID: 2066, Accession: Q15303 |
Catalog # | 7773-5 |
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Order / More Info | ErbB4/HER4 (His Tagged), Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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