产品详情 |
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Antigenic Specificity | CD86 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD86(CD86) detection. Tested with WB in Mouse. No cross reactivity with other proteins. CD86 is officially called Cluster of Differentiation 86, also known as B7-2. Being a member of the immunoglobulin superfamily, it is a protein expressed on antigen-presenting cells. The CD86 gene is mapped to human chromosome 3q21. The smallest transcript, 828 bp, which the authors termed CD86deltaTM, has a deletion from nucleotide 686 to nucleotide 829(i.e., exon 6) and encodes a 275-amino acid protein. CD86deltaTM enhances proliferation and cytokine production by both naive and memory T cells, providing costimulatory signals necessary for T cell activation and survival. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD86(66-80aa YEHYLGTEKLDSVNA), different from the related rat sequence by two amino acids. |
Other Names | T-lymphocyte activation antigen CD86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;CD86;Cd86; |
Gene, Accession # | CD86, UniProt: P42082 |
Catalog # | PA1394 |
Price | |
Order / More Info | CD86 Antibody from BOSTER BIO |
Product Specific References | n/a |
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