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Product Name | Recombinant Porcine IL-4 (carrier-free) |
Description | L-4 is the primary cytokine implicated in the development of Th2-mediated responses, which is associated with allergy and asthma. The Type I receptor comprises IL-4Rα and the common gamma-chain (γc), which is also shared by the cytokines IL-2, -7, -9, -15 and -21 and is present in hematopoietic cells. IL-4 can use the type II complex, comprising IL-4Rα and IL-13Rα1, which is present in non-hematopoietic cells. This second receptor complex is a functional receptor for IL-13, which shares approximately 25% homology with IL-4. The type I receptor complex can be formed only by IL-4 and is active in Th2 development. In contrast, the type II receptor complex formed by either IL-4 or IL-13 is more active during airway hypersensitivity and mucus secretion and is not found in T cells. |
Size | 5 µg |
Concentration | n/a |
Applications | BA |
Other Names | B cell growth factor 1 (BCGF-1), B-cell stimulatory factor 1 (BSF-1), B cell growth factor 1, interleukin-4, lymphocyte stimulatory factor 1. |
Gene, Accession, CAS # | Gene ID: 397225 |
Catalog # | 782801 |
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Order / More Info | Recombinant Porcine IL-4 (carrier-free) from BIOLEGEND |
Product Specific References | n/a |
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