| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Smad4 |
|---|
| Clone | RM277 |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG |
|---|
| Format | affinity purified |
|---|
| Size | 50 µl |
|---|
| Concentration | n/a |
|---|
| Applications | WB, IHC |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Monoclonal antibody to detect Smad4 in human samples. Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throµgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. |
|---|
| Immunogen | A peptide corresponding to the C-terminus of human Smad4 |
|---|
| Other Names | SMAD family member, Mothers against decapentaplegic homolog, MAD homolog, Mothers against DPP homolog, SMAD4 |
|---|
| Gene, Accession # | Gene ID: 4089, Accession: Q9BYG6 |
|---|
| Catalog # | A1605-50 |
|---|
| Price | |
|---|
| Order / More Info | Smad4 Antibody from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|