产品详情 |
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Antigenic Specificity | Smad7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | 0.5 mg/ml |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Smad7 Antibody. Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throµgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. |
Immunogen | Synthetic peptide from human Smad 7 |
Other Names | SMAD7 , MADH7, MADH8 , Smad7; hSMAD7; SMAD family member 7 |
Gene, Accession # | Gene ID: 4092, Accession: AAB81354.1 |
Catalog # | 3670-100 |
Price | |
Order / More Info | Smad7 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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