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Product Name | RAP2B, Recombinant, Human, aa1-183, His-Tag |
Description | Purity ~95% (SDS-PAGE). Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Source: Recombinant protein corresponding to human RAP2B, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~22.9kD (206aa) (MALDI-TOF) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMREYKVV VLGSGGVGKS ALTVQFVTGS FIEKYDPTIE DFYRKEIEVD SSPSVLEILD TAGTEQFASM RDLYIKNGQG FILVYSLVNQ QSFQDIKPMR DQIIRVKRYE RVPMILVGNK VDLEGEREVS YGEGKALAEE WSCPFMETSA KNKASV |
Size | 100ug |
Concentration | n/a |
Applications | n/a |
Other Names | RAP2B, Recombinant, Human, aa1-183, His-Tag (Ras-related Protein Rap-2b, RAP2B, Member of RAS Oncogene Family) |
Gene, Accession, CAS # | n/a |
Catalog # | 137176 |
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Order / More Info | RAP2B, Recombinant, Human, aa1-183, His-Tag from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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