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Product Name | Purine Nucleoside Phosphorylase Activity Assay Kit (Fluorometric) |
Description | Purine Nucleoside Phosphorylase (PNP) (E.C. 2.4.2.1.) is an enzyme involved in purine metabolism and it catalyzes the cleavage of the glycosidic bond of ribo- or deoxyribonucleosides, in the presence of inorganic phosphate as a second substrate, to generate the purine base and ribose-1-phosphate or deoxyribose-1-phosphate. It is one of the enzymes of the nucleotide salvage pathways that allows the cell to produce nucleotide monophosphates when the de novo synthesis pathway has been interrupted or is non-existent (as is the case in the brain). PNP is a cytosolic enzyme. PNP deficiency disease leads to toxic buildup of deoxyguanosine in T-cells leading to T-lymphocytopenia with no apparent effects on B-lymphocyte function. Inhibition of PNP i |
Size | 100 assays |
Concentration | n/a |
Applications | Detection of Purine Nucleoside Phosphorylase activity in variety of samples |
Other Names | PNP Activity Assay Kit (Fluorometric) |
Gene, Accession, CAS # | n/a |
Catalog # | K767-100 |
Price | |
Order / More Info | Purine Nucleoside Phosphorylase Activity Assay Kit (Fluorometric) from BIOVISION, INC. |
Product Specific References | n/a |
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